| Hydroxyethyl Cellulose (HEC) |
Nonionic, water-soluble cellulose ether |
Water-based personal care, household, coating, and pharmaceutical formulations where broad compatibility and a smooth texture are required |
Approximately 3–10; viscosity is generally stable across mildly acidic to mildly alkaline conditions |
Generally good tolerance to common salts and surfactants because it is nonionic; high electrolyte levels can still reduce viscosity |
Hydrate gradually in cool or moderately warm water. Prolonged exposure to very high temperatures may reduce polymer performance |
Use moderate agitation. Pre-wetting can reduce fish-eyes and lump formation; excessive air entrainment should be avoided |
Select a grade suitable for the intended use and verify applicable food, cosmetic, pharmaceutical, or industrial requirements. Review the current SDS and impurity specifications |
Hydration can be slow; excessive shear or unsuitable addition order may produce inconsistent viscosity |
| Hydroxypropyl Methylcellulose (HPMC) |
Nonionic cellulose ether with methoxy and hydroxypropyl substitution |
Water-based gels, suspensions, oral products, construction mixtures, and formulations requiring film formation or thermal gel behavior |
Approximately 3–11, depending on grade and formulation composition |
Usually compatible with moderate electrolyte levels, but salts and solvents can alter hydration, gelation, and final viscosity |
Some grades exhibit reversible thermal gelation when heated. Avoid uncontrolled heating and allow adequate cooling before final viscosity evaluation |
Disperse carefully to prevent clumping. High-shear mixing may be used for dispersion but can introduce air and should be controlled |
Use only grades authorized for the target application. For pharmaceutical or food use, confirm monograph, residual solvent, microbial, and heavy-metal requirements |
Viscosity is strongly affected by temperature and grade selection; delayed hydration may complicate batch release testing |
| Carboxymethyl Cellulose (CMC) |
Anionic, water-soluble cellulose derivative |
Suspensions, detergents, food systems, oral formulations, and water-based products requiring water retention and pseudoplastic flow |
Approximately 4–10; performance may decline under strongly acidic conditions |
Moderate salt tolerance. Divalent and trivalent ions, such as calcium and magnesium, can reduce viscosity or cause incompatibility |
Generally processed at ambient or moderate temperatures. Excessive heat, prolonged residence time, or extreme pH can accelerate degradation |
Add slowly into well-agitated water. Adequate hydration time is important; excessive shear may lower molecular weight and viscosity |
For food or pharmaceutical applications, confirm the relevant legal status, purity specifications, allergen controls, and microbial limits in the target market |
Not ideal for high-hardness water or systems containing high levels of multivalent ions; may interact with cationic ingredients |
| Carbomer |
Cross-linked polyacrylic acid polymer |
Clear aqueous gels, topical products, sanitizing gels, and formulations requiring high thickening efficiency at low use levels |
Usually approximately 5–10 after neutralization; viscosity is low before neutralization |
Low to moderate tolerance. Electrolytes, acidic actives, and high levels of solvents can significantly reduce viscosity |
Disperse before neutralization. Avoid excessive heat and prolonged high-shear processing, which may reduce viscosity or clarity |
Use controlled mixing to prevent polymer fisheyes and air entrapment. Neutralize gradually with a suitable base while monitoring pH |
Check residual monomer specifications, preservative compatibility, skin or mucosal safety data, and the applicable cosmetic or pharmaceutical regulations |
Highly sensitive to salts and some active ingredients; requires pH adjustment and may produce stringy or overly stiff gels if overdosed |
| Acrylates/C10-30 Alkyl Acrylate Crosspolymer |
Cross-linked acrylic polymer with hydrophobic modification |
Emulsions, creams, lotions, and surfactant-containing systems requiring suspension, yield value, and improved emulsion stability |
Typically approximately 4–10 after neutralization, depending on grade and formulation |
Low to moderate tolerance. Electrolytes, cationic materials, and high surfactant concentrations can lower viscosity |
Hydrate under controlled conditions and neutralize near the end of processing. Avoid unnecessary heat and excessive shear after viscosity development |
Use moderate mixing and allow full polymer wetting. Neutralization rate and order of addition strongly affect final rheology |
Confirm applicable cosmetic regulations, residual monomer limits, preservative performance, and compatibility with the intended leave-on or rinse-off use |
Can lose viscosity in electrolyte-rich formulas; poor neutralization control may cause instability, haze, or batch-to-batch variation |
| Xanthan Gum |
Microbial polysaccharide produced by fermentation |
Food, personal care, household, and technical water-based systems requiring suspension, pseudoplastic flow, and freeze-thaw support |
Approximately 2–12; generally functional over a broad pH range, subject to formulation and storage conditions |
Good tolerance to many salts and electrolytes compared with acrylic polymers; very high ionic strength can still change texture and viscosity |
Usually stable under moderate heating. Extended high-temperature exposure, severe acidity, or oxidative conditions may reduce performance |
Disperse into a non-solvent or pre-blend with dry ingredients before hydration. High shear can improve dispersion but may reduce viscosity if prolonged |
Use an appropriate purified grade and verify microbial specifications, allergen statements, residual processing aids, and regulatory status for the intended market |
May create a stringy or slimy sensory profile; can form lumps when added directly to water without adequate dispersion |
| Sclerotium Gum |
Fermentation-derived neutral polysaccharide |
Skin-care emulsions, gels, and natural-positioned formulations requiring a smooth, elastic, and stable rheological profile |
Approximately 3–12, depending on the complete formulation |
Generally good compatibility with moderate electrolyte levels and many surfactants; compatibility should be confirmed in concentrated systems |
Typically processed with moderate heating and sufficient hydration time. Avoid prolonged severe heat or oxidative exposure |
Pre-disperse thoroughly and hydrate before final viscosity assessment. Moderate shear is normally sufficient |
Verify fermentation controls, microbial limits, preservative compatibility, and any natural or organic claim requirements independently |
Usually more expensive than common cellulose or synthetic polymers; hydration and final texture depend strongly on grade and process order |
| Hydroxypropyl Starch Phosphate |
Modified starch derivative |
Food, personal care, and topical systems requiring body, suspension, water binding, and a powdery or less tacky sensory finish |
Approximately 4–10, depending on grade and application |
Generally moderate tolerance to salts; high ionic strength, acids, or strong bases may affect swelling and viscosity |
Many grades require heating to swell and develop viscosity. Follow the supplier’s specified temperature profile and avoid excessive thermal holding |
Disperse before heating to minimize lumps. Controlled agitation is needed during gelatinization and cooling |
Confirm source, modification method, allergen status, residual contaminants, and the applicable food, cosmetic, or pharmaceutical requirements |
Performance depends on heating and cooling history; viscosity may change during storage or under repeated freeze-thaw cycles |
| Associative Polyurethane Thickener |
Hydrophobically modified, water-dispersible polyurethane polymer |
Water-based coatings, inks, adhesives, and selected personal care systems requiring flow control and shear-thinning behavior |
Often approximately 6–10, but the optimum range is grade- and formulation-dependent |
Variable. Surfactants, solvents, salts, and other hydrophobically modified polymers can strongly affect association and viscosity |
Generally processed at ambient or moderate temperatures. Avoid freezing and uncontrolled high-temperature storage; follow the product’s technical limits |
Add slowly under moderate agitation. High shear, surfactant level, and order of addition can materially change the final rheology |
Review SDS information, residual monomer or solvent data, VOC requirements, worker exposure controls, and application-specific regulations |
Formulation-dependent behavior can make prediction difficult; incompatible surfactants or solvents may cause viscosity loss or phase separation |